Majid Asadi-Shekaari; Alireza Saied; Mohammad Mahdi Molaei; Jalil Abshenas; Omid Gholipoor Bashiri; Alia Ayatollahi Moussavi
Abstract
Background: The
standard method for repair of an injured peripheal nerve is epineural repair
with separate sutures. In this article, we described a method of continuous
running epineural suturing in an animal model, and compared
it with the standard interrupted technique. Methods: In a clinical ...
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Background: The
standard method for repair of an injured peripheal nerve is epineural repair
with separate sutures. In this article, we described a method of continuous
running epineural suturing in an animal model, and compared
it with the standard interrupted technique. Methods: In a clinical trial study, the sciatic nerve of 25 dogs was cut by a sharp blade
under general anesthesia. The dogs were randomly divided in 3 groups. The 10
dogs received simple interrupted suturing of the cut sciatic nerve (control
group), another 10 had continuous suturing technique, and the remaining 5 were
left unrepaired. After 6 weeks the dogs were sacrificed and the nerves were
studied by light and electron microscopy. The amount of consumed suture
material, time of repair, myelin thickness and axon diameter were examined.
Ultrastructural studies were performed to assess the degeneration and
regeneration process. Results: The time of suturing and the amount
of consumed suture material were significantly lower in the continous group (p < /i>
